HEALTH EFFECTS|Endocrine Toxicity References

Endocrine Toxicity References
There is no generally accepted source for an authoritative list of chemicals that are recognized to cause endocrine toxicity.

Environmental Defense's list of suspect endocrine toxicants is compiled from the following sources:

ATSDR: Agency for Toxic Substances and Disease Registry. Minimal risk Levels for Hazardous Substances. January 2004.

BKH: BKH/European Commission. Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: - preparation of a candidate list of substances as a basis for priority setting. Final report-November 2000. Category 1 chemicals from Annex 1: Candidate list of 553 substances.

BRUC: Brucker-Davis, F. Effects of Environmental Synthetic Chemicals on Thyroid Function. Thyroid. 8(9): 827-856. 1998.

EDF: See Environmental Defense's Custom Hazard Identification documentation.

EPA-HEN: US EPA, Air Risk Information Support Center. Health Effects Notebook for Hazardous Air Pollutants.

EPA-SDWA: UUS EPA. Announcement of the Draft Drinking Water Contaminant Candidate List; Notice. 62 Federal Register 52193-52219 (October 6, 1997). (Table 6).

EPA-TRI: US EPA. Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right to Know. Proposed and Final Rules. 59 Federal Register 1788 (Jan 12, 1994); 59 Federal Register 61432 (November 30, 1994). Summarized in Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion.

GUIL: Guillette, L. J., and E. Guillette. Environmental Contaminants and Reproductive Abnormalities in Wildlife: Implications for Public Health? Toxicology and Industrial Health. 12(3): 537-550. 1996.

IL-EPA: Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro).

JNIHS: Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals.

KEIT: Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997.,,0471191450%7Cdesc%7C3037,00.html

NJ-FS: New Jersey Department of Health Services. Right to Know Program, NJDOH, Trenton, NJ.

OEHHA-CREL: California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document "Determination of Noncancer Chronic Reference Exposure Levels". Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (, plus draft CRELS proposed through March 2004 (

RTECS: National Institute for Occupational Safety and Health's Registry of Toxic Effects of Chemical Substances. See Environmental Defense's Suspect Hazard Identification documentation.

WWF: World Wildlife Fund. Our Stolen Future. Widespread Pollutants with Endocrine-disrupting Effects. The WWF list is derived from references detailed at and was originally published in: Colborn, T., F.S. vom Saal, and A.M. Soto. Developmental Effects of Endocrine-Disrupting Chemicals In Wildlife and Humans. Environmental Health Perspectives 101(5): 378-384. 1993.