Cancer References
P65: The most current and authoritative list of chemicals
that are recognized to cause cancer is California's
Proposition 65. Substances are placed on the Proposition
65 list of chemicals "known to the state of
California to cause cancer" if an independent science
advisory board has concluded they possess sufficient
evidence of carcinogenicity in animals or humans, or if an
authoritative organization such as the
International Agency for Research on Cancer or the National
Toxicology Program have reached a similar
conclusion, or if a federal regulatory agency requires a
cancer warning label. The current Proposition 65 List of Carcinogens (July 2004) can be obtained from http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html.
A number of chemicals have toxicological evidence of
carcinogenicity that currently does not satisfy the
sufficiency criteria used to list agents under Proposition
65, or that has not yet been finally evaluated by the
carcinogen identification processes in the state of
California or other authoritative agencies.
Environmental Defense's list of suspect carcinogens is compiled from the
following sources:
CPDB: Carcinogenic Potency Database. http://potency.berkeley.edu/app14.html
Environmental Defense reviewed this compilation of results on carcinogenicity
in rats and mice covering 1298 chemicals and
added any chemical with positive results in at least two
species by a relevant route of exposure to its list of
suspect carcinogens.
EDF: See Environmental Defense's Custom Hazard
Identification documentation.
EPA-HEN: US EPA, Air Risk Information Support Center. Health
Effects Notebook for Hazardous Air
Pollutants. http://www.epa.gov/ttnatw01/hlthef/hapindex.html
EPA-TRI: US EPA. Addition of Certain Chemicals; Toxic Chemical Release
Reporting; Community Right to Know. Proposed and Final Rules. 59
Federal Register 1788 (Jan 12, 1994); 59 Federal
Register 61432 (November 30, 1994). Summarized in Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion. http://www.epa.gov/tri/chemical/hazard_cx.htm
HAZMAP: A Relational Database of Hazardous Chemicals and Occupational Diseases. Browse Haz-Map by Adverse Effects: Carcinogen (Known, Probable, Possible) and Lung Toxin-Lung Cancer. http://hazmap.nlm.nih.gov/hazmapadv.html
IARC: World Health Organization, International Agency for Research on
Cancer. IARC Monographs Programme on the Evaluation of
Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can
be obtained at http://monographs.iarc.fr/monoeval/grlist.html.
IRIS: US EPA, National Center for Environmental Assessment. Integrated Risk Information System. http://www.epa.gov/iriswebp/iris/index.html
NTP-BR: National Toxicology Program. Summary for Agents, Substances, Mixtures or Exposure Circumstances to be Reviewed in 2001-2002 for Possible Listing in the Report on Carcinogens, Eleventh Edition. NTP Board of Scientific Counselors, NTP, Research Triangle Park, NC.http://ntp-server.niehs.nih.gov/NewHomeRoc/11thConsideration.html
National Toxicology Program. Summary for Agents, Substances, Mixtures or Exposure Circumstances to be Reviewed in 2004-2005 for Possible Listing in the Report on Carcinogens, Twelfth Edition. NTP
Board of Scientific Counselors, NTP, Research Triangle Park, NC. http://ntp-server.niehs.nih.gov/NewHomeRoc/12thConsideration.html
NTP-C: National Toxicology Program. 10th Report on Carcinogens
(2002). http://ehis.niehs.nih.gov/roc/toc10.html
NTP-HS: National Toxicology Program. Chemical Repository of Health and Safety Data. http://ntp-db.niehs.nih.gov/NTP_Reports/NTP_Chem_H&S/NTP_Chem8/Radian[Insert CAS#].txt
OEHHA-TCD: California Environmental Protection Agency, Office of Environmental Health Hazard Assessment. Toxicity Criteria Database - OEHHA Cancer Potency Values
. http://www.oehha.ca.gov/risk/pdf/60204cascpl.pdf.
OPP-CAN: US EPA, Office of Pesticide Programs. List of Chemicals Evaluated
for Carcinogenic Potential (5/10/2002). OPP, Washington, DC. http://www.epi.uci.edu/valleycenter/EPAListCarcinogenicChemicals.pdf
ORD-SF: US EPA, Office of Research and Development, Superfund Health Risk
Technical Support Center. Risk Assessment Issue Paper for:
Toxicity Information and Provisional Oral Slope Factor for
Nitroglycerin. ORD, Washington, DC.
P65-CAND: California EPA, Office of Environmental Health Hazard Assessment. Prioritization Notices.
http://www.oehha.org/prop65/CRNR_notices/state_listing/prioritization_notices/index.html.
Chemicals on Candidate List for consideration under Proposition 65 due to
high carcinogenicity concern (through March 2004).
Chemicals under consideration for listing via the authoritative
bodies mechanisms (through July 2004).
P65-MC: Hazard identification based on an extension of a
Proposition 65 listing. Substance is either a member of a
class that is a recognized Proposition 65 hazard, or is a
class that contains a member that is a recognized Propositon
65 hazard. See Environmental Defense's Member Class
Hazard Identification documentation.
P65-PEND: California EPA, Office of Environmental Health Hazard
Assessment. Notices of Intent to List . http://www.oehha.org/prop65/CRNR_notices/admin_listing/intent_to_list/index.html.
Chemicals noticed for listing under Proposition 65 because a body considered to be authoritative by the state's qualified experts has formally identified it as causing cancer (through July 2004).
SCDM: US EPA, Office of Emergency Response and Remediation.
Superfund Chemical Data Matrix.
http://www.epa.gov/superfund/resources/scdm/index.htm
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