HEALTH EFFECTS|Kidney Toxicants

Kidney Toxicants
Exposure to chemical substances can cause adverse effects on the kidney, ureter, or bladder (Kidney Toxicity). The kidney is unusually susceptible because of its role in filtering harmful substances from the blood. Toxic injury to the kidney is known to occur as a result of exposures to halogenated hydrocarbons, such as carbon tetrachloride and trichloroethylene, and the heavy metals cadmium and lead. Some of these toxicants cause acute injury to the kidney, while others produce chronic changes that can lead to end-stage renal failure or cancer.