HEALTH EFFECTS|Musculoskeletal Toxicants

Musculoskeletal Toxicants
Exposure to chemical substances can cause adverse effects on the muscles, bones, and joints (Musculoskeletal Toxicity). The bone disorders arthritis, fluorosis, and osteomalacia are among the musculoskeletal diseases that can be induced by occupational or environmental toxicants. Rheumatoid arthritis is an autoimmune disease of the connective tissue characterized by joint inflammation and pain. It is often chronic and progressive, leading to deformities and disability. Prolonged exposure to silica and coal dust increases its incidence. Occupational exposure to fluoride can cause the skeletal disorder fluorosis, in which fluoride rather than calcium is deposited in bone. Osteomalacia is a painful, degenerative disease involving the gradual softening and bending of bones. It is caused by exposure to the musculoskeletal toxicant cadmium.

References used to compile the list of Musculoskeletal Toxicants


Suspected Musculoskeletal Toxicants Note: For your convenience, these data are also available as a CSV file. Click here to download.
Chemical Name CAS Registry Number (or EDF Substance ID) Reference(s)
1-(4-SULFOPHENYL)-4-((4-SULFOPHENYL)AZO)-1H-PYRAZOLE-3-CARBOXYLIC1934-21-0RTECS
4 NQO56-57-5RTECS
ACETYLSALICYLIC ACID50-78-2RTECS
ALUMINUM HYDRATE WASTES UNDER CLASS 6.1 - TDGR21645-51-2RTECS
ARSENIC OXIDE (3)1327-53-3RTECS
ATENOLOL29122-68-7RTECS
AZATHIOPRINE446-86-6RTECS
CAFFEINE58-08-2RTECS
CARBARYL63-25-2EPA-HEN
CHLOROBENZENE108-90-7EPA-HEN
CHLOROETHANE75-00-3EPA-HEN
CLOFIBRATE637-07-0RTECS
DAPSONE80-08-0RTECS
DISULFIRAM97-77-8RTECS
DOXYCYCLINE564-25-0RTECS
FLUORIDE16984-48-8OEHHA-CREL
HYDROCHLORIC ACID7647-01-0EPA-HEN
HYDROFLUORIC ACID7664-39-3EPA-HEN, OEHHA-CREL
ISOTRETINOIN4759-48-2RTECS
MEPHENYTOIN50-12-4RTECS
MINOCYCLINE HYDROCHLORIDE (INTERNAL USE)13614-98-7RTECS
PENICILLAMINE52-67-5RTECS
PHOSPHINE7803-51-2EPA-HEN
PHOSPHORUS (YELLOW OR WHITE)7723-14-0EPA-HEN
PROCAINAMIDE51-06-9RTECS
RADIUMRAV000EPA-HEN
SELENIUM7782-49-2EPA-HEN
SELENIUM COMPOUNDSSBP500EPA-HEN
SELENIUM SULFIDE7446-34-6EPA-HEN
SODIUM FLUORIDE7681-49-4ATSDR, RTECS
STRONTIUM7440-24-6ATSDR
SULFURIC ACID7664-93-9RTECS
TETRACYCLINE HYDROCHLORIDE64-75-5EPA-TRI
ZEARALENONE17924-92-4RTECS

[ top ]

If you would like to change the way this page displays data, you may click here to personalize your Scorecard.