HEALTH EFFECTS|DEVELOPMENTAL TOXICANTS

DEVELOPMENTAL TOXICANTS
Developmental toxicants are agents that cause adverse effects on the developing child. Effects can include birth defects, low birth weight, biological dysfunctions, or psychological or behavioral deficits that become manifest as the child grows. Maternal exposure to toxic chemicals during pregnancy can disrupt the development or even cause the death of the fetus. Exposure of pregnant women to mercury, lowers birth weight and can cause severe brain damage in children. While developmental toxicity usually results from prenatal exposures to toxicants experienced by the mother, it can also result from paternal exposures. For example, the occupational exposure of men to vinyl chloride has been associated with increased rates of spontaneous abortion in their wives. Early postnatal contact with toxicants can also affect normal development. Exposure to secondhand tobacco smoke, for example, increases an infant's risk of contracting respiratory infections or succumbing to sudden infant death syndrome.

References used to compile the list of Developmental Toxicants


Suspected Developmental Toxicants Note: For your convenience, these data are also available as a CSV file. Click here to download.
Chemical Name CAS Registry Number (or EDF Substance ID) Reference(s)
(2AE,4E,8E)-(5'S,6S,6'R,7S,11R,13S,15S,17AR,20R,20AR,20BS)-6'-((S- )-SEC-BUTYL)-5',6,6',7,10,11,14,15,17A,20,20A,20B-DODECAHYDRO-20,- 20B-DIHYDROXY-5',6,8,19-TETRAMETHYL-17-OXOSPIRO(11,15-METHANO-2H,- 13H,17H-FURO(4,3,2-PQ)(2,6)BENZODIOXACYCLOOCTADEC[...65195-55-3P65-PEND
1,1,1-TRICHLOROETHANE71-55-6EPA-SARA
1,1,2,2-TETRACHLOROETHANE79-34-5EPA-SARA
1,1-DICHLOROETHYLENE75-35-4EPA-SARA, JANK
1,2,4-TRICHLOROBENZENE120-82-1EPA-SARA
1,2-BENZENEDICARBOXYLIC ACID, DI-C8- 10-BRANCHED ALKYL ESTERS, C9-RICH68515-48-0CERHR
1,2-BENZENEDICARBOXYLIC ACID, DI-C9- 11-BRANCHED ALKYL ESTERS, C10-RICH68515-49-1CERHR
1,2-BENZENEDICARBOXYLIC ACID, DIISODECYL ESTER26761-40-0CERHR, P65-CAND
1,2-BENZENEDICARBOXYLIC ACID, DIISONONYL ESTER28553-12-0CERHR
1,2-DIBROMO-3-CHLOROPROPANE (DBCP)96-12-8EPA-SARA
1,2-DICHLOROETHANE107-06-2EPA-SARA
1,2-ETHANEDIAMINE, N,N'-BIS(2-AMINOETHYL)-112-24-3JANK
1,3-DIMETHYLUREA96-31-1JANK
1,4-DICHLOROBENZENE106-46-7ATSDR, JANK
1-BROMOPROPANE106-94-5P65-CAND
1-HEXANOL, 2-ETHYL-104-76-7JANK
1-HYDROXY-2-PHENOXYETHANE122-99-6NTP-R
2,4-D94-75-7EPA-SARA
2,4-D 2-ETHYL-4-METHYLPENTYL ESTER53404-37-8EPA-TRI
2,4-D 2-ETHYLHEXYL ESTER1928-43-4EPA-TRI
2,4-D BUTYL ESTER94-80-4JANK
2,4-D, ISOOCTYL ESTER25168-26-7JANK
2,4-DB94-82-6EPA-TRI, P65-CAND
2,4-DINITROPHENOL51-28-5EPA-SARA
2,4-DP120-36-5EPA-TRI, JANK, P65-PEND
2-CHLOR-1,3-BUTADIENE126-99-8EPA-SARA
2-METHOXYPROPYL-1-ACETATE70657-70-4JANK
2-NITROPROPANE79-46-9EPA-SARA
2-PHENYLPHENOL90-43-7EPA-SARA
ABAMECTIN71751-41-2EPA-TRI, P65-PEND
ACETALDEHYDE75-07-0JANK
ACETIC ACID, INDOLYL-87-51-4JANK
ACETONITRILE75-05-8EPA-SARA, JANK
ACROLEIN107-02-8JANK
ACRYLONITRILE107-13-1ATSDR, EPA-SARA
ALACHLOR15972-60-8EPA-TRI
ALBUTEROL18559-94-9P65-CAND
ALDRIN309-00-2ATSDR, EPA-SARA, JANK
ALKANES, CHLORO61788-76-9P65-MC
ALLYL CHLORIDE107-05-1EPA-SARA
AMINONICOTINAMIDE329-89-5JANK
AMITROLE61-82-5JANK
ANILAZINE101-05-3EPA-TRI
AROMATIC NAPHTHA, TYPE I64742-95-6JANK
ARSENIC (ORGANIC OR INORGANIC COMPOUNDS)ARF750OEHHA-CREL, P65-MC
ARSENIC COMPOUNDSARF-750OEHHA-CREL
ATORVASTATIN CALCIUM134523-03-8P65-CAND
BAPN151-18-8JANK
BAPN FUMARATE2079-89-2JANK
BARIUM7440-39-3EPA-SARA
BENZO(A)PYRENE50-32-8JANK, P65-PEND
BENZOIC TRICHLORIDE98-07-7EPA-SARA
BENZOYL CHLORIDE98-88-4EPA-SARA
BENZYL BUTYL PHTHALATE85-68-7CERHR, P65-CAND
BENZYL CHLORIDE100-44-7EPA-SARA
BIPHENYL92-52-4EPA-SARA
BIS(TRIBUTYLTIN) OXIDE56-35-9JANK
BORON7440-42-8ATSDR
BROMINE COMPOUNDS (ORGANIC OR INORGANIC)EDF-227P65-MC
CACODYLIC ACID75-60-5JANK
CADMIUM CHLORIDE10108-64-2JANK
CADMIUM COMPOUNDSCAE750JANK, P65-MC
CAMPHECHLOR8001-35-2EPA-SARA, JANK
CAPTAN133-06-2EPA-SARA, JANK
CARBARYL63-25-2EPA-SARA, JANK
CARBON DIOXIDE124-38-9JANK
CARBON TETRACHLORIDE56-23-5EPA-SARA, OEHHA-AREL, OEHHA-CREL
CESIUM7440-46-2ATSDR
CHLORAMPHENICOL56-75-7JANK
CHLORDANE57-74-9ATSDR, EPA-SARA
CHLORINE DIOXIDE10049-04-4EPA-SARA, JANK
CHLOROBENZENE108-90-7JANK
CHLORODIFLUOROMETHANE75-45-6OEHHA-CREL
CHLOROETHANE75-00-3ATSDR, OEHHA-CREL
CHLOROFORM67-66-3EPA-SARA, JANK, OEHHA-AREL, OEHHA-CREL
COBALT7440-48-4ATSDR
COPPER7440-50-8EPA-SARA
CYANIDE57-12-5EPA-SARA
CYCLOHEXANONE108-94-1JANK
DDT (TOTAL)EDF-229P65-MC
DECABROMODIPHENYL OXIDE1163-19-5EPA-SARA
DELTA-8,9-ISOMER OF AVERMECTINEDF-376P65-PEND
DIAMINOTOLUENE (MIXED ISOMERS)25376-45-8JANK
DIAZINON333-41-5EPA-TRI, JANK
DIBENZOFURANS (CHLORINATED)1080OEHHA-CREL
DIBUTYL PHTHALATE84-74-2ATSDR, CERHR, EPA-SARA, JANK, NTP-R, P65-CAND
DICAMBA1918-00-9EPA-TRI
DICHLORVOS62-73-7EPA-SARA, JANK
DIETHYLENE GLYCOL DIMETHYL ETHER111-96-6JANK
DIETHYLENE GLYCOL ETHER111-46-6JANK
DIETHYLENE GLYCOL MONOMETHYL ETHER111-77-3JANK
DIMETHOATE60-51-5EPA-TRI, JANK
DIMETHYL CHLOROTHIOPHOSPHATE2524-03-0EPA-TRI
DIMETHYLAMINE DICAMBA2300-66-5EPA-TRI
DIOXIN AND DIOXIN-LIKE COMPOUNDSEDF-018P65-MC
DIPHENYL-P-PHENYLENEDIAMINE74-31-7JANK
DIRECT BLUE 62602-46-2EPA-SARA
DISODIUM HYDROGEN ARSENATE7778-43-0OEHHA-CREL
DISULFIRAM97-77-8JANK
DISULFOTON298-04-4ATSDR
DIURON330-54-1EPA-TRI
EK 7011123-39-7JANK
ERGOCALCIFEROL50-14-6JANK
ETHANOL64-17-5JANK
ETHYL ACRYLATE140-88-5EPA-SARA
ETHYLBENZENE100-41-4ATSDR, EPA-SARA, OEHHA-CREL
ETHYLENE GLYCOL107-21-1ATSDR, NTP-R, OEHHA-CREL
ETHYLENE GLYCOL DIETHYL ETHER629-14-1JANK
ETHYLENE GLYCOL DIMETHYL ETHER110-71-4JANK
ETHYLENE GLYCOL MONOBUTYL ETHER111-76-2JANK
ETHYLENE GLYCOL MONOPROPYL ETHER2807-30-9JANK
ETHYLENE OXIDE75-21-8EPA-SARA, JANK
FELODIPINE72509-76-3P65-CAND
FENBUTATIN OXIDE13356-08-6EPA-TRI, P65-PEND
FENOXYCARB72490-01-8EPA-TRI
FERBAM14484-64-1JANK
FLUOXETINE54910-89-3CERHR
FLUOXETINE HYDROCHLORIDE59333-67-4CERHR
FLUVASTATIN SODIUMEDF-004P65-CAND
FOLPET133-07-3JANK
GAMMA-LINDANE58-89-9ATSDR, EPA-SARA
GLUTARALDHYDE111-30-8JANK
GLYCOL ETHERSEDF-109P65-MC
GRISEOFULVIN126-07-8JANK
HEAVY METALSEDF-380P65-MC
HEXACHLORO-1,3-BUTADIENE87-68-3EPA-SARA, JANK
HEXACHLOROCYCLOPENTADIENE77-47-4EPA-SARA
HEXACHLOROETHANE67-72-1EPA-SARA
HEXACHLOROPHENE (HCP)70-30-4JANK
HYDRAZINE302-01-2JANK
HYDROFLUORIC ACID7664-39-3EPA-SARA
IMAZALIL35554-44-0EPA-TRI, JANK
IMIDAN732-11-6JANK
INORGANIC BROMINE COMPOUNDSEDF-015P65-MC
ISOPHORONE78-59-1OEHHA-CREL
ISOPROPYL ALCOHOL67-63-0OEHHA-CREL
LEWISITE (ARSENIC COMPOUND)541-25-3JANK
M-XYLENE108-38-3EPA-SARA, JANK
MANEB12427-38-2EPA-SARA, JANK
METALSEDF-035P65-MC
METHANAMINE, N-METHYL-N-NITROSO62-75-9JANK
METHANOL67-56-1CERHR, JANK, OEHHA-CREL
METHOXYCHLOR72-43-5EPA-HEN, EPA-SARA
METHOXYFLURANE76-38-0JANK
METHYL ETHYL KETONE78-93-3EPA-SARA, JANK
METHYL ISOBUTYL KETONE108-10-1JANK
METHYL ISOCYANATE624-83-9EPA-HEN, EPA-SARA, JANK
METHYL METHACRYLATE80-62-6EPA-SARA
METRIBUZIN21087-64-9EPA-TRI, P65-PEND
MOLINATE2212-67-1EPA-TRI
MUSTARD GAS505-60-2ATSDR
N,N-DIMETHYLFORMAMIDE68-12-2JANK, NTP-R
N-ETHYL-N-NITROSOUREA759-73-9EPA-SARA
N-HEXANE110-54-3JANK
N-NITROSO-N-METHYLUREA684-93-5EPA-SARA, JANK
N-NITROSODIETHYLAMINE55-18-5EPA-SARA, JANK
N-NITROSOMORPHOLINE59-89-2EPA-SARA
NAPHTHALENE91-20-3EPA-HEN, EPA-SARA
NICKEL7440-02-0EPA-SARA
NICKEL COMPOUNDSNDB000P65-MC
NITROFEN1836-75-5EPA-SARA, JANK
NITROFURANTOIN67-20-9NTP-R
NITROGEN DIOXIDE10102-44-0CAA-AQC
NITROUS OXIDE10024-97-2JANK
O-XYLENE95-47-6EPA-SARA, JANK
ORGANIC BROMINE COMPOUNDSEDF-226P65-MC
ORGANOCHLORINE PESTICIDESEDF-175P65-MC
P-XYLENE106-42-3EPA-SARA, JANK
PARATHION56-38-2EPA-SARA
PENTACHLOROPHENOL87-86-5ATSDR, EPA-SARA, OEHHA-CREL
PHENOL108-95-2EPA-SARA, JANK
PHTHALATESEDF-150P65-MC
PM 10EDF-077P65-MC
PM 2.5EDF-213P65-MC
POLYCHLORINATED DIBENZO-P-DIOXINSPCDDP65-MC
POLYCHLORINATED TERPHENYLS61788-33-8JANK
POTASSIUM IODIDE7681-11-0JANK
POTASSIUM N-METHYLDITHIOCARBAMATE137-41-7EPA-TRI
PROPACHLOR1918-16-7EPA-TRI
PROPYLENE OXIDE75-56-9EPA-SARA
QUINTOZENE82-68-8EPA-SARA
RADIONUCLIDES1165P65-MC
RONNEL299-84-3JANK
SACCHARIN81-07-2EPA-SARA
SELENIUM7782-49-2EPA-SARA
SIMVASTATIN79902-63-9P65-PEND
SODIUM CHLORITE7758-19-2JANK
SODIUM DICAMBA1982-69-0EPA-TRI
SODIUM FLUORIDE7681-49-4JANK
SODIUM IODIDE7681-82-5JANK
SODIUM NITRITE7632-00-0EPA-TRI
SOLUBLE NICKEL COMPOUNDS7440-02-0(Sol)P65-MC
STYRENE100-42-5EPA-SARA, JANK
STYRENE OXIDE96-09-3EPA-SARA, JANK
SULFUR DIOXIDE7446-09-5JANK
SULPROFOS35400-43-2EPA-TRI
TEBUTHIURON34014-18-1EPA-TRI
TERT-BUTYL ALCOHOL75-65-0JANK
TETRACHLOROETHYLENE127-18-4ATSDR, EPA-SARA
TETRAHYDROFURAN109-99-9JANK
THIABENDAZOLE148-79-8EPA-TRI, JANK
THIADIAZOLE, 2,2'-(METHYLENEDIIMINO)BIS, 1,3,4-26907-37-9JANK
THIOUREA62-56-6EPA-SARA, JANK
THIRAM137-26-8JANK
TOLUENESULFONAMIDE, O-88-19-7JANK
TRIBUTYLTIN COMPOUNDSEDF-184P65-MC
TRICHLORFON52-68-6EPA-SARA, JANK
TRICHLOROETHYLENE79-01-6ATSDR, EPA-HEN, EPA-SARA, JANK
TRIETHYLENE GLYCOL112-27-6JANK
TRIETHYLENE GLYCOL DIMETHYL ETHER112-49-2JANK, NTP-R
TRIFLURALIN1582-09-8EPA-SARA, JANK
TRIS(2,3-DIBROMOPROPYL) PHOSPHATE126-72-7EPA-SARA
VINYL CHLORIDE75-01-4ATSDR, EPA-SARA, JANK
VISIBILITY REDUCING PARTICULATESEDF-214P65-MC
VOLATILE ORGANIC COMPOUNDSEDF-111P65-MC
WOOD PRESERVATIVES (CONTAINING ARSENIC & CHROMATE)1206P65-MC
XYLENE (MIXED ISOMERS)1330-20-7ATSDR, EPA-SARA, JANK
ZEARALENONE17924-92-4P65-PEND
ZINC7440-66-6EPA-SARA
ZINC SULFATE7733-02-0JANK

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